zvad fmk zvad Search Results


apoptosis inhibitor zvad-fmk  (SCAPS GmbH)
90
SCAPS GmbH apoptosis inhibitor zvad-fmk
Apoptosis Inhibitor Zvad Fmk, supplied by SCAPS GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/apoptosis inhibitor zvad-fmk/product/SCAPS GmbH
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apoptosis inhibitor zvad-fmk - by Bioz Stars, 2026-02
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tnfa/ carbobenzoxyvalyl-alanyl-aspartyl-[o-methyl]-fluoromethylketone (zvad.fmk)/smac mimetic  (SMAC Corp)
90
SMAC Corp tnfa/ carbobenzoxyvalyl-alanyl-aspartyl-[o-methyl]-fluoromethylketone (zvad.fmk)/smac mimetic
Tnfa/ Carbobenzoxyvalyl Alanyl Aspartyl [O Methyl] Fluoromethylketone (Zvad.Fmk)/Smac Mimetic, supplied by SMAC Corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/tnfa/ carbobenzoxyvalyl-alanyl-aspartyl-[o-methyl]-fluoromethylketone (zvad.fmk)/smac mimetic/product/SMAC Corp
Average 90 stars, based on 1 article reviews
tnfa/ carbobenzoxyvalyl-alanyl-aspartyl-[o-methyl]-fluoromethylketone (zvad.fmk)/smac mimetic - by Bioz Stars, 2026-02
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zvad-fmk  (Adooq Bioscience LLC)
90
Adooq Bioscience LLC zvad-fmk
Zvad Fmk, supplied by Adooq Bioscience LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zvad-fmk/product/Adooq Bioscience LLC
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zvad-fmk - by Bioz Stars, 2026-02
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zvad-fmk  (Promega)
90
Promega zvad-fmk
Zvad Fmk, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zvad-fmk/product/Promega
Average 90 stars, based on 1 article reviews
zvad-fmk - by Bioz Stars, 2026-02
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zvad-fmk  (Enzo Biochem)
90
Enzo Biochem zvad-fmk
Zvad Fmk, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zvad-fmk/product/Enzo Biochem
Average 90 stars, based on 1 article reviews
zvad-fmk - by Bioz Stars, 2026-02
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n-benzyl-oxycarbonyl-val-ala-asp-fluoromethylketone (z-vad-fmk  (Kamiya)
90
Kamiya n-benzyl-oxycarbonyl-val-ala-asp-fluoromethylketone (z-vad-fmk
N Benzyl Oxycarbonyl Val Ala Asp Fluoromethylketone (Z Vad Fmk, supplied by Kamiya, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/n-benzyl-oxycarbonyl-val-ala-asp-fluoromethylketone (z-vad-fmk/product/Kamiya
Average 90 stars, based on 1 article reviews
n-benzyl-oxycarbonyl-val-ala-asp-fluoromethylketone (z-vad-fmk - by Bioz Stars, 2026-02
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zvad  (Merck KGaA)
90
Merck KGaA zvad
Zvad, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zvad/product/Merck KGaA
Average 90 stars, based on 1 article reviews
zvad - by Bioz Stars, 2026-02
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zvad-fmk  (Bachem)
90
Bachem zvad-fmk
Zvad Fmk, supplied by Bachem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zvad-fmk/product/Bachem
Average 90 stars, based on 1 article reviews
zvad-fmk - by Bioz Stars, 2026-02
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zvad.fmk  (Avantor)
90
Avantor zvad.fmk
a Prophylactic vaccination model assessing the immunogenicity of ferroptosis. ML162-induced ferroptosis (5 μM, 14 h), in comparison with apoptosis (1000 IU/ml TNF + 10 μM TAK1i, 14 h) and necroptosis (1000 IU/ml TNF + 10 μM TAK1i + 10 μM <t>zVAD.fmk,</t> 24 h). OVA-expressing non-tumorigenic MEF cells (BM1-OVA) were used as a vaccine and live ovalbumin expressing melanoma cells (B16-OVA) were used as challenge. Kaplan–Meier curves represent the effectiveness of ferroptotic cells in preventing the tumor growth at the challenge site. Data were analyzed by Kaplan–Meier simple survival analysis. b Tumor size of B16-OVA derived melanoma after vaccination with BM1-OVA cells. Data presented as mean ± SEM. c Scheme of the therapeutic vaccination experiment. Conventional dendritic cells type 1 (cDC1) carrying ferroptotic or necroptotic cargo were intradermally injected in melanoma tumor-bearing mice. d B16-OVA tumor size progression of animals receiving either cDC1 with ferroptotic (5 μM, 14 h) or necroptotic (1000 IU/ml TNF + 10 μM TAK1i + 10 μM zVAD.fmk, 24 h) cargo. Data presented as mean ± SEM. Statistical significance was determined by two-sided t-test on each day of measurement. e Comparison of euthanasia time determined by the size of the tumor. Kaplan–Meier curves show the time of euthanasia, Data analyzed by Kaplan–Meier simple survival analysis. f Prophylactic vaccination model using either Mitoxantrone-treated MCA205 cells (1 μM, 24 h) or Mitoxantrone-treated MCA205 mixed with ML162-killed cells (0.5 µM, 14 h). Kaplan–Meier curves show the percentage of tumor-free mice after the challenge with live cancer cells. Data were analyzed by Kaplan–Meier simple survival analysis.
Zvad.Fmk, supplied by Avantor, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zvad.fmk/product/Avantor
Average 90 stars, based on 1 article reviews
zvad.fmk - by Bioz Stars, 2026-02
90/100 stars
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carbobenzoxy-valylalanyl-aspartyl-[o-methyl]-fluoromethylketone (z-vad-fmk  (Becton Dickinson)
90
Becton Dickinson carbobenzoxy-valylalanyl-aspartyl-[o-methyl]-fluoromethylketone (z-vad-fmk
a Prophylactic vaccination model assessing the immunogenicity of ferroptosis. ML162-induced ferroptosis (5 μM, 14 h), in comparison with apoptosis (1000 IU/ml TNF + 10 μM TAK1i, 14 h) and necroptosis (1000 IU/ml TNF + 10 μM TAK1i + 10 μM <t>zVAD.fmk,</t> 24 h). OVA-expressing non-tumorigenic MEF cells (BM1-OVA) were used as a vaccine and live ovalbumin expressing melanoma cells (B16-OVA) were used as challenge. Kaplan–Meier curves represent the effectiveness of ferroptotic cells in preventing the tumor growth at the challenge site. Data were analyzed by Kaplan–Meier simple survival analysis. b Tumor size of B16-OVA derived melanoma after vaccination with BM1-OVA cells. Data presented as mean ± SEM. c Scheme of the therapeutic vaccination experiment. Conventional dendritic cells type 1 (cDC1) carrying ferroptotic or necroptotic cargo were intradermally injected in melanoma tumor-bearing mice. d B16-OVA tumor size progression of animals receiving either cDC1 with ferroptotic (5 μM, 14 h) or necroptotic (1000 IU/ml TNF + 10 μM TAK1i + 10 μM zVAD.fmk, 24 h) cargo. Data presented as mean ± SEM. Statistical significance was determined by two-sided t-test on each day of measurement. e Comparison of euthanasia time determined by the size of the tumor. Kaplan–Meier curves show the time of euthanasia, Data analyzed by Kaplan–Meier simple survival analysis. f Prophylactic vaccination model using either Mitoxantrone-treated MCA205 cells (1 μM, 24 h) or Mitoxantrone-treated MCA205 mixed with ML162-killed cells (0.5 µM, 14 h). Kaplan–Meier curves show the percentage of tumor-free mice after the challenge with live cancer cells. Data were analyzed by Kaplan–Meier simple survival analysis.
Carbobenzoxy Valylalanyl Aspartyl [O Methyl] Fluoromethylketone (Z Vad Fmk, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/carbobenzoxy-valylalanyl-aspartyl-[o-methyl]-fluoromethylketone (z-vad-fmk/product/Becton Dickinson
Average 90 stars, based on 1 article reviews
carbobenzoxy-valylalanyl-aspartyl-[o-methyl]-fluoromethylketone (z-vad-fmk - by Bioz Stars, 2026-02
90/100 stars
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zvad.fmk  (Becton Dickinson)
90
Becton Dickinson zvad.fmk
a Prophylactic vaccination model assessing the immunogenicity of ferroptosis. ML162-induced ferroptosis (5 μM, 14 h), in comparison with apoptosis (1000 IU/ml TNF + 10 μM TAK1i, 14 h) and necroptosis (1000 IU/ml TNF + 10 μM TAK1i + 10 μM <t>zVAD.fmk,</t> 24 h). OVA-expressing non-tumorigenic MEF cells (BM1-OVA) were used as a vaccine and live ovalbumin expressing melanoma cells (B16-OVA) were used as challenge. Kaplan–Meier curves represent the effectiveness of ferroptotic cells in preventing the tumor growth at the challenge site. Data were analyzed by Kaplan–Meier simple survival analysis. b Tumor size of B16-OVA derived melanoma after vaccination with BM1-OVA cells. Data presented as mean ± SEM. c Scheme of the therapeutic vaccination experiment. Conventional dendritic cells type 1 (cDC1) carrying ferroptotic or necroptotic cargo were intradermally injected in melanoma tumor-bearing mice. d B16-OVA tumor size progression of animals receiving either cDC1 with ferroptotic (5 μM, 14 h) or necroptotic (1000 IU/ml TNF + 10 μM TAK1i + 10 μM zVAD.fmk, 24 h) cargo. Data presented as mean ± SEM. Statistical significance was determined by two-sided t-test on each day of measurement. e Comparison of euthanasia time determined by the size of the tumor. Kaplan–Meier curves show the time of euthanasia, Data analyzed by Kaplan–Meier simple survival analysis. f Prophylactic vaccination model using either Mitoxantrone-treated MCA205 cells (1 μM, 24 h) or Mitoxantrone-treated MCA205 mixed with ML162-killed cells (0.5 µM, 14 h). Kaplan–Meier curves show the percentage of tumor-free mice after the challenge with live cancer cells. Data were analyzed by Kaplan–Meier simple survival analysis.
Zvad.Fmk, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zvad.fmk/product/Becton Dickinson
Average 90 stars, based on 1 article reviews
zvad.fmk - by Bioz Stars, 2026-02
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zvad.fmk  (ApexBio)
90
ApexBio zvad.fmk
a Prophylactic vaccination model assessing the immunogenicity of ferroptosis. ML162-induced ferroptosis (5 μM, 14 h), in comparison with apoptosis (1000 IU/ml TNF + 10 μM TAK1i, 14 h) and necroptosis (1000 IU/ml TNF + 10 μM TAK1i + 10 μM <t>zVAD.fmk,</t> 24 h). OVA-expressing non-tumorigenic MEF cells (BM1-OVA) were used as a vaccine and live ovalbumin expressing melanoma cells (B16-OVA) were used as challenge. Kaplan–Meier curves represent the effectiveness of ferroptotic cells in preventing the tumor growth at the challenge site. Data were analyzed by Kaplan–Meier simple survival analysis. b Tumor size of B16-OVA derived melanoma after vaccination with BM1-OVA cells. Data presented as mean ± SEM. c Scheme of the therapeutic vaccination experiment. Conventional dendritic cells type 1 (cDC1) carrying ferroptotic or necroptotic cargo were intradermally injected in melanoma tumor-bearing mice. d B16-OVA tumor size progression of animals receiving either cDC1 with ferroptotic (5 μM, 14 h) or necroptotic (1000 IU/ml TNF + 10 μM TAK1i + 10 μM zVAD.fmk, 24 h) cargo. Data presented as mean ± SEM. Statistical significance was determined by two-sided t-test on each day of measurement. e Comparison of euthanasia time determined by the size of the tumor. Kaplan–Meier curves show the time of euthanasia, Data analyzed by Kaplan–Meier simple survival analysis. f Prophylactic vaccination model using either Mitoxantrone-treated MCA205 cells (1 μM, 24 h) or Mitoxantrone-treated MCA205 mixed with ML162-killed cells (0.5 µM, 14 h). Kaplan–Meier curves show the percentage of tumor-free mice after the challenge with live cancer cells. Data were analyzed by Kaplan–Meier simple survival analysis.
Zvad.Fmk, supplied by ApexBio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/zvad.fmk/product/ApexBio
Average 90 stars, based on 1 article reviews
zvad.fmk - by Bioz Stars, 2026-02
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Image Search Results


a Prophylactic vaccination model assessing the immunogenicity of ferroptosis. ML162-induced ferroptosis (5 μM, 14 h), in comparison with apoptosis (1000 IU/ml TNF + 10 μM TAK1i, 14 h) and necroptosis (1000 IU/ml TNF + 10 μM TAK1i + 10 μM zVAD.fmk, 24 h). OVA-expressing non-tumorigenic MEF cells (BM1-OVA) were used as a vaccine and live ovalbumin expressing melanoma cells (B16-OVA) were used as challenge. Kaplan–Meier curves represent the effectiveness of ferroptotic cells in preventing the tumor growth at the challenge site. Data were analyzed by Kaplan–Meier simple survival analysis. b Tumor size of B16-OVA derived melanoma after vaccination with BM1-OVA cells. Data presented as mean ± SEM. c Scheme of the therapeutic vaccination experiment. Conventional dendritic cells type 1 (cDC1) carrying ferroptotic or necroptotic cargo were intradermally injected in melanoma tumor-bearing mice. d B16-OVA tumor size progression of animals receiving either cDC1 with ferroptotic (5 μM, 14 h) or necroptotic (1000 IU/ml TNF + 10 μM TAK1i + 10 μM zVAD.fmk, 24 h) cargo. Data presented as mean ± SEM. Statistical significance was determined by two-sided t-test on each day of measurement. e Comparison of euthanasia time determined by the size of the tumor. Kaplan–Meier curves show the time of euthanasia, Data analyzed by Kaplan–Meier simple survival analysis. f Prophylactic vaccination model using either Mitoxantrone-treated MCA205 cells (1 μM, 24 h) or Mitoxantrone-treated MCA205 mixed with ML162-killed cells (0.5 µM, 14 h). Kaplan–Meier curves show the percentage of tumor-free mice after the challenge with live cancer cells. Data were analyzed by Kaplan–Meier simple survival analysis.

Journal: Nature Communications

Article Title: Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity

doi: 10.1038/s41467-022-31218-2

Figure Lengend Snippet: a Prophylactic vaccination model assessing the immunogenicity of ferroptosis. ML162-induced ferroptosis (5 μM, 14 h), in comparison with apoptosis (1000 IU/ml TNF + 10 μM TAK1i, 14 h) and necroptosis (1000 IU/ml TNF + 10 μM TAK1i + 10 μM zVAD.fmk, 24 h). OVA-expressing non-tumorigenic MEF cells (BM1-OVA) were used as a vaccine and live ovalbumin expressing melanoma cells (B16-OVA) were used as challenge. Kaplan–Meier curves represent the effectiveness of ferroptotic cells in preventing the tumor growth at the challenge site. Data were analyzed by Kaplan–Meier simple survival analysis. b Tumor size of B16-OVA derived melanoma after vaccination with BM1-OVA cells. Data presented as mean ± SEM. c Scheme of the therapeutic vaccination experiment. Conventional dendritic cells type 1 (cDC1) carrying ferroptotic or necroptotic cargo were intradermally injected in melanoma tumor-bearing mice. d B16-OVA tumor size progression of animals receiving either cDC1 with ferroptotic (5 μM, 14 h) or necroptotic (1000 IU/ml TNF + 10 μM TAK1i + 10 μM zVAD.fmk, 24 h) cargo. Data presented as mean ± SEM. Statistical significance was determined by two-sided t-test on each day of measurement. e Comparison of euthanasia time determined by the size of the tumor. Kaplan–Meier curves show the time of euthanasia, Data analyzed by Kaplan–Meier simple survival analysis. f Prophylactic vaccination model using either Mitoxantrone-treated MCA205 cells (1 μM, 24 h) or Mitoxantrone-treated MCA205 mixed with ML162-killed cells (0.5 µM, 14 h). Kaplan–Meier curves show the percentage of tumor-free mice after the challenge with live cancer cells. Data were analyzed by Kaplan–Meier simple survival analysis.

Article Snippet: Cell death inhibitors zVAD.fmk (#BACE4026865.0005, VWR International, Belgium) and Nec-1s (synthesized by the Laboratory of Medicinal Chemistry; University of Antwerp, Belgium) were used at 10 μM, Fer1 (#M60042-2s, Xcess Biosciences, USA) was used at 0,5 μM and DFO (#D-9533, Sigma-Aldrich, USA) at 50 μM.

Techniques: Expressing, Derivative Assay, Injection